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Name Price Add to Cart Adipex 37.5mg (30 pills) 49.88 Adipex 37.5mg (60 pills) 94.88 Adipex 37.5mg (90 pills) 144.88 IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. COMMON BRAND NAME(S): Fastin, Ionamin, Plegine, Prelu-2, Sanorex, Tenuate USES: This medication is used in combination with a diet plan to help you reduce weight. HOW TO USE: This medication is best taken on an empty stomach one hour before meals. Sustained-release or long acting products must be swallowed whole. Crushing or chewing them will destroy the long action and may cause increased side effects. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. It is usually taken for 8 to 12 weeks. Use in combination with other appetite suppressant medicine is generally not recommended. Consult your doctor before such use. SIDE EFFECTS: Blurred vision, dizziness, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. If these effects persist or become bothersome, inform your doctor. Notify your doctor if you experience: chest pain, nervousness, pounding heart, difficulty urinating, mood changes, breathing difficulties, swelling. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. If you notice other effects not listed above, contact your doctor or pharmacist. PRECAUTIONS: Tell your doctor your complete medical history, especially if you have: high blood pressure, an over-active thyroid, glaucoma, diabetes, emotional problems. This medication can be habit forming and must be used with caution. Alcohol can increase unwanted side effects of dizziness. Limit alcohol use. This drug is not recommended for use in children. Consult your doctor or pharmacist for further information. This medication should be used only when clearly needed during pregnancy. Discuss the risk and benefits with your doctor. This drug may be excreted into breast milk. You may have to stop nursing or stop using this drug. Consult your doctor before breast-feeding. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take: high blood pressure medicine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), any other weight loss medicine. Avoid "stimulant" drugs that may increase your heart rate such as decongestants or caffeine. Decongestants are commonly found in over-the-counter cough-and-cold medicines. Do not start or stop any medicine without doctor or pharmacist approval. OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include restlessness, fever, fast breathing, dizziness, confusion, hallucinations, panic or paranoid, drowsiness, convulsions, unconsciousness, unusually fast or slow heart beat, headache, nausea/vomiting, diarrhea, stomach pain, pale or flushing, chest pain, sweating, muscle weakness, agitation, large pupils, or delusions. NOTES: Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. Do not share this medication with others. MISSED DOSE: If you miss a dose, do not double the next dose. Instead, skip the missed dose and resume your usual dosing schedule. STORAGE: Store at room temperature away from sunlight and moisture. Do not store in the bathroom. Adipex 37.5mg (30 pills) 49.94 Adipex 37.5mg (60 pills) 94.94 Adipex 37.5mg (90 pills) 144.94 IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug. APPETITE SUPPRESSANTS - ORAL COMMON BRAND NAME(S): Fastin, Ionamin, Plegine, Prelu-2, Sanorex, Tenuate USES: This medication is used in combination with a diet plan to help you reduce weight. HOW TO USE: This medication is best taken on an empty stomach one hour before meals. Sustained-release or long acting products must be swallowed whole. Crushing or chewing them will destroy the long action and may cause increased side effects. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. It is usually taken for 8 to 12 weeks. Use in combination with other appetite suppressant medicine is generally not recommended. Consult your doctor before such use. SIDE EFFECTS: Blurred vision, dizziness, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. If these effects persist or become bothersome, inform your doctor. Notify your doctor if you experience: chest pain, nervousness, pounding heart, difficulty urinating, mood changes, breathing difficulties, swelling. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. If you notice other effects not listed above, contact your doctor or pharmacist. PRECAUTIONS: Tell your doctor your complete medical history, especially if you have: high blood pressure, an over-active thyroid, glaucoma, diabetes, emotional problems. This medication can be habit forming and must be used with caution. Alcohol can increase unwanted side effects of dizziness. Limit alcohol use. This drug is not recommended for use in children. Consult your doctor or pharmacist for further information. This medication should be used only when clearly needed during pregnancy. Discuss the risk and benefits with your doctor. This drug may be excreted into breast milk. You may have to stop nursing or stop using this drug. Consult your doctor before breast-feeding. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take: high blood pressure medicine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), any other weight loss medicine. Avoid "stimulant" drugs that may increase your heart rate such as decongestants or caffeine. Decongestants are commonly found in over-the-counter cough-and-cold medicines. Do not start or stop any medicine without doctor or pharmacist approval. OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include restlessness, fever, fast breathing, dizziness, confusion, hallucinations, panic or paranoid, drowsiness, convulsions, unconsciousness, unusually fast or slow heart beat, headache, nausea/vomiting, diarrhea, stomach pain, pale or flushing, chest pain, sweating, muscle weakness, agitation, large pupils, or delusions. NOTES: Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. Do not share this medication with others. MISSED DOSE: If you miss a dose, do not double the next dose. Instead, skip the missed dose and resume your usual dosing schedule. STORAGE: Store at room temperature away from sunlight and moisture. Do not store in the bathroom. PHENTERMINE Pill Medication Dosage Quantity/Supply Price Order Phentermine 37.5 (Adipex) 37.5 Mg 30 Tablets (1 Month) $55.00 $109.00 Phentermine 37.5 (Adipex) 37.5 Mg 60 Tablets (2 Months) $77.00 $149.00 Phentermine 37.5 (Adipex) 37.5 Mg 90 Tablets (3 Months) $93.00 $179.00 Phentermine Blue & Clear (Fastin) 30 Mg 30 Capsules (1 Month) $69.00 $85.00 Phentermine Blue & Clear (Fastin) 30 Mg 60 Capsules (2 Months) $87.00 $107.00 Phentermine Blue & Clear (Fastin) 30 Mg 90 Capsules (3 Months) $103.00 $149.00 Phentermine Yellow (Ionamin) 30 Mg 30 Capsules (1 Month) $69.00 $85.00 Phentermine Yellow (Ionamin) 30 Mg 60 Capsules (2 Months) $87.00 $107.00 Phentermine Yellow (Ionamin) 30 Mg 90 Capsules (3 Months) $103.00 $149.00 Phentermine 15 Mg 30 Capsules (1 Month) $47.99 $85.00 Phentermine 15 Mg 60 Capsules (2 Months) $79.99 $107.00 Phentermine 15 Mg 90 Capsules (3 Months) $91.99 $149.00 TENUATE Pill Medication Dosage Quantity/Supply Price Order Tenuate (Generic) 25 Mg 90 Tablets (1 Month) $59.00 $159.00 Tenuate (Generic) 75 Mg 30 Tablets (1 Month) $45.00 $59.00 Tenuate (Generic) 75 Mg 60 Tablets (2 Months) $90.00 $109.00 Tenuate (Generic) 75 Mg 90 Tablets (3 Months) $149.00 $159.00 MERIDIA Pill Medication Dosage Quantity/Supply Price Order Meridia 10 Mg 30 Capsules (1 Month) $118.00 $177.00 Meridia 10 Mg 60 Capsules (2 Month) $220.00 $279.00 Meridia 10 Mg 90 Capsules (3 Months) $290.00 $350.00 Meridia 15 Mg 30 Capsules (1 Month) $138.00 $234.00 Meridia 15 Mg 60 Capsules (2 Months) $276.00 $334.00 Meridia 15 Mg 90 Capsules (3 Months) $414.00 $534.00 XENICAL Pill Medication Dosage Quantity/Supply Price Order Xenical 120 Mg 90 Capsules (1 Month) $139.00 $236.00 Xenical 120 Mg 180 Capsules (2 Months) $260.00 $441.00 Xenical 120 Mg 270 Capsules (3 Months Adipex-P This page contains drug information on Adipex-P. The information provided includes the following: what is Adipex-P the possible side effects of Adipex-P what happens if you miss a dose of Adipex-P what happens if you overdose with Adipex-P the most important information about Adipex-P how to use Adipex-P other drugs that may affect Adipex-P what to avoid while using Adipex-P Generic Name: phentermine (FEN ter meen) Brand Names: Adipex-P, Fastin, Ionamin, Obenix, Obephen, Oby-Cap, Oby-Trim, Panshape M, Phentercot, Phentride, Pro-Fast HS, Pro-Fast SA, Pro-Fast SR, Teramine, Zantryl What is the most important information I should know about phentermine? • Use caution when driving, operating machinery, or performing other hazardous activities. Phentermine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Phentermine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Do not crush, chew or open any "once-daily" phentermine tablets or capsules. Swallow them whole. What is phentermine? • Phentermine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or "anorexigenic" drug. Phentermine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. • Phentermine is used as a short-term supplement to diet and exercise in the treatment of obesity. • Phentermine may also be used for purposes other than those listed in this medication guide. Who should not take phentermine? • You cannot take phentermine if you · have heart disease or high blood pressure; · have arteriosclerosis (hardening of the arteries); · have glaucoma; · have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or · have a history of drug or alcohol abuse. • Before taking this medication, tell your doctor if you have · problems with your thyroid, · an anxiety disorder, · epilepsy or another seizure disorder, or · diabetes. • You may not be able to take phentermine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. • It is not known whether phentermine will harm an unborn baby. Do not take phentermine without first talking to your doctor if you are pregnant. • It is also not known whether phentermine passes into breast milk. Do not take phentermine without first talking to your doctor if you are breast-feeding a baby. How should I take phentermine? • Take phentermine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. • Phentermine is usually taken once or twice a day before a meal on an empty stomach. • Do not take phentermine in the evening because it may cause insomnia. • Do not crush, chew or open any "once-daily" phentermine tablets or capsules. Swallow them whole. • Never take more of this medication than is prescribed for you. Too much phentermine could be very dangerous to your health. • Store phentermine at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a phentermine overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. What should I avoid while taking phentermine? • Use caution when driving, operating machinery, or performing other hazardous activities. Amphetamine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Do not take phentermine late in the day. A dose taken too late in the day can cause insomnia. What are the possible side effects of phentermine? • If you experience any of the following serious side effects, stop taking phentermine and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or · hallucinations, abnormal behavior, or confusion. • Other, less serious side effects may be more likely to occur. Continue to take phentermine and talk to your doctor if you experience · restlessness or tremor, · nervousness or anxiety, · headache or dizziness, · insomnia, · dry mouth or an unpleasant taste in your mouth, · diarrhea or constipation, or · impotence or changes in your sex drive. • Phentermine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect phentermine? • You cannot take phentermine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days. • Changes in insulin and other diabetes drug therapies may be necessary during treatment with phentermine. • Phentermine may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine. • Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of phentermine. • Drugs other than those listed here may also interact with phentermine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Where can I get more information? • Your pharmacist has more information about phentermine written for health professionals that you may read. -------------------------------------------------------------------------------- • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/ or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. 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Adipex florida: Adipex weight loss. ... News release. Adipex side effects. Available Information About 30 days to a Consultation to abandon ... enables regulators to date. Adipex info . In addition, the process of possible ... web.1asphost.com PDR Drug information for Adipex-P Capsules Manufacturer: Gate DESCRIPTION Phentermine hydrochloride USP has the chemical name of (alpha),(alpha)-Dimethylphenethylamine hydrochloride. The structural formula is as follows: Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether. ADIPEX-P®, an anorectic agent for oral administration, is available as a capsule or tablet containing 37.5 mg ofphentermine hydrochloride (equivalent to 30 mg ofphentermine base). ADIPEX-P® Capsules contain the inactive ingredients Corn Starch, Gelatin, Lactose Monohydrate, Magnesium Stearate, Titanium Dioxide, Black Iron Oxide, FD&C Blue #1, FD&C Red #40 and D&C Red #33. ADIPEX-P® Tablets contain the inactive ingredients Corn Starch, Lactose (Anhydrous), Magnesium Stearate, Microcrystalline Cellulose, Pregelatinized Starch, Sucrose, and FD&C Blue #1. CLINICAL PHARMACOLOGY ADIPEX-P® is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics." It has not been established that the action of such drugs in treating obesity is primarily one of appetite suppression. Other central nervous system actions, or metabolic effects, may be involved, for example. Adult obese subjects instructed in dietary management and treated with "anorectic" drugs lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a fraction of a pound a week. The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. The possible origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed. Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of obesity is measured in years, whereas the studies cited are restricted to a few weeks' duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. INDICATIONS AND USAGE ADIPEX-P® (phentermine hydrochloride) is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index >/=30 kg/m 2 , or >/=27 kg/m 2 in the presence of other risk factors (e.g., hypertension, diabetes, hyperlipidemia). Below is a chart of Body Mass Index (BMI) based on various heights and weights. BMI is calculated by taking the patient's weight, in kilograms (kg), divided by the patient's height, in meters (m), squared. Metric conversions are as follows: pounds ? 2.2 = kg; inches ? 0.0254 = meters. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY ) should be measured against possible risk factors inherent in their use such as those described below. CONTRAINDICATIONS Advanced arteriosclerosis, cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma. Agitated states. Patients with a history of drug abuse. During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).

WARNINGS ADIPEX-P® is indicated only as short-term monotherapy for the management of exogenous obesity. The safety and efficacy of combination therapy with phentermine and any other drug products for weight loss, including selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Therefore, coadministration of these drug products for weight loss is not recommended. Primary Pulmonary Hypertension (PPH)--a rare, frequently fatal disease of the lungs--has been reported to occur in patients receiving a combination of phentermine with fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken phentermine alone. The initial symptom of PPH is usually dyspnea. Other initial symptoms include: angina pectoris, syncope or lower extremity edema. Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema. Valvular Heart Disease: Serious regurgitant cardiac valvular disease, primarily affecting the mitral, aortic and/or tricuspid valves, has been reported in otherwise healthy persons who had taken a combination of phentermine with fenfluramine or dexfenfluramine for weight loss. The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. The possibility of an association between valvular heart disease and the use of phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken phentermine alone. Tolerance to the anorectic effect usually develops within a few weeks. When this occurs, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued. ADIPEX-P® may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly. DRUG ABUSE AND DEPENDENCE ADIPEX-P® is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of ADIPEX-P® should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia. Usage with Alcohol: Concomitant use of alcohol with ADIPEX-P® may result in an adverse drug interaction. PRECAUTIONS General Caution is to be exercised in prescribing ADIPEX-P® (phentermine hydrochloride) for patients with even mild hypertension. Insulin requirements in diabetes mellitus may be altered in association with the use of ADIPEX-P® and the concomitant dietary regimen. ADIPEX-P® may decrease the hypotensive effect of guanethidine. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Carcinogenesis, Mutagenesis, Impairment of Fertility: Studies have not been performed with ADIPEX-P® (phentermine hydrochloride) to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. Pregnancy--Teratogenic Effects: Pregnancy Category C. Animal reproduction studies have not been conducted with ADIPEX-P®. It is also not known whether ADIPEX-P® can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. ADIPEX-P® should be given to a pregnant woman only if clearly needed. Nursing Mothers Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use Safety and effectiveness in pediatric patients have not been established. ADVERSE REACTIONS Cardiovascular: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease (see WARNINGS ), palpitation, tachycardia, elevation of blood pressure. Central Nervous System: Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache; rarely psychotic episodes at recommended doses. Gastrointestinal: Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Allergic: Urticaria. Endocrine: Impotence, changes in libido. OVERDOSAGE Manifestations of acute overdosage with phentermine include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma. Management of acute phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases phentermine excretion. Intravenous phentolamine (Regitine®, CIBA) has been suggested for possible acute, severe hypertension, if this complicates phentermine overdosage. DOSAGE AND ADMINISTRATION Exogenous Obesity: Dosage should be individualized to obtain an adequate response with the lowest effective dose. The usual adult dose is one capsule or tablet (37.5 mg) daily, administered before breakfast or 1-2 hours after breakfast. For tablets, the dosage may be adjusted to the patient's need. For some patients ? tablet (18.75 mg) daily may be adequate, while in some cases it may be desirable to give ? tablet (18.75 mg) two times a day. Late evening medication should be avoided because of the possibility of resulting insomnia. Phentermine is not recommended for use in patients sixteen (16) years of age and under. HOW SUPPLIED Available in tablets and capsules containing 37.5 mgphentermine hydrochloride (equivalent to 30 mgphentermine base). Each blue and white, oblong, scored tablet is debossed with "ADIPEX-P" and "9"-"9". The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with "ADIPEX-P" - "37.5" on the cap and two stripes on the body using dark blue ink. Tablets are packaged in bottles of 30 (NDC 57844-009-56); 100 (NDC 57844-009-01); and 1000 (NDC 57844-009-10). Capsules are packaged in bottles of 100 (NDC 57844-019-01). Store at controlled room temperature 15°-30°C (59°-86°F) (see USP). Dispense in a tight container as defined in the USP, with a child-resistant closure (as required). 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Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Phentermine SALE! (generic medication) Drug Name # of pills Dosage Price(USD) Click Phentermine 100 37.5 mg $71.95 Phentermine 30 30 mg $45.00 Interested in a natural weight loss supplement? CLICK HERE Adipex-RX Your weightloss medication Source Experience Superb Fast Weight Loss Like Never Before With FDA approved Prescription Medications like Adipex®. 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Any opinions expressed on the Site are the opinions of the authors. Adipex-RX.com does not assume any liability for the contents of any material provided on the Site. Reliance on any information provided by Adipex-RX.com, its Health Experts, commentators or other visitors to the site is solely at your own risk. Adipex-RX.com assumes no liability or responsibility for damage or injury to persons or property arising from any use of any product, information, idea, or instruction contained in the materials provided to you. Adipex-RX.com reserves the right to change or discontinue at any time any aspect or feature of this site. You access this material at your own risk. Adipex-RX.com , its licensers and its suppliers have no control over and accept no responsibility whatsoever for such materials. Phentermine 90 pills $108 Free Shipping Save up to 70% on your prescription medications. Visit our pharmacy for convenient and cost-effective way of buying generic drugs. We offer free prescription and delivery worldwide. http://www.rxgenericdrugs.com/phentermine.htm [today's views: 1] Buy Phentermine (Adipex) Online Get the lowest prices on Phentermine (Adipex) and Herbal Phentermine. Find the best online pharmacies here. http://www.the-info-planet.com/phentermine.htm [today's views: 1] Websites Listings and Reviews for adipex Check out adipex websites at Giantexplorer. All sites reviewed and divided into categories. Also lots of adipex related websites reviewed. http://www.giantexplorer.com [today's views: 1] adipex The most popular sites for adipex! http://www.upspiral.com [today's views: 1] adipex on The Best Broadband Site on the Internet Heavy.com is the best broadband site on the internet, offering the best free videos, music and so much more. Check it out! http://www.heavy.com [today's views: 1] Facts about adipex at Answers.com Get smart about adipex at Answers.com. We collect facts from name-brand reference titles for you, for free. http://www.answers.com [today's views: 1] Adipex aka Fastin, Ionamin (Phentermine) Adipex aka Fastin, Ionamin (Phentermine), Appetite Supressants, Weight Loss & Diet Pills: This page is a prescription and over the counter drug index. You'll find Free Drug Consultation, Free Drug Resources prescriptionforviagra.com [today's views: 1] Top 10 Websites for Adipex The top Websites for Adipex - the best Suppliers and shippers of such medications. Check out each of these websites for the best deals, discounts, prices and information and order your supplies. (FEN ter meen) Adipex-P, Fastin, Ionamin, Obenix, Obephen, Oby-Cap, Oby-Trim, Panshape M, Phentercot, Phentride, Pro-Fast HS, Pro-Fast SA, Pro-Fast SR, Teramine, Zantryl What is the most important information I should know about Adipex? • Use caution when driving, operating machinery, or performing other hazardous activities. Adipex may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Adipex is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Do not crush, chew or open any "once-daily" Adipex tablets or capsules. Swallow them whole. What is Adipex? • Adipex is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or "anorexigenic" drug. Adipex stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. • Adipex is used as a short-term supplement to diet and exercise in the treatment of obesity. • Adipex may also be used for purposes other than those listed in this medication guide. Who should not take Adipex? • You cannot take Adipex if you · have heart disease or high blood pressure; · have arteriosclerosis (hardening of the arteries); · have glaucoma; · have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or · have a history of drug or alcohol abuse. • Before taking this medication, tell your doctor if you have · problems with your thyroid, · an anxiety disorder, · epilepsy or another seizure disorder, or · diabetes. • You may not be able to take Adipex, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. • It is not known whether Adipex will harm an unborn baby. Do not take Adipex without first talking to your doctor if you are pregnant. • It is also not known whether Adipex passes into breast milk. Do not take Adipex without first talking to your doctor if you are breast-feeding a baby. How should I take Adipex? • Take Adipex exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. • Adipex is usually taken once or twice a day before a meal on an empty stomach. • Do not take Adipex in the evening because it may cause insomnia. • Do not crush, chew or open any "once-daily" Adipex tablets or capsules. Swallow them whole. • Never take more of this medication than is prescribed for you. Too much Adipex could be very dangerous to your health. • Store Adipex at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Adipex overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. What should I avoid while taking Adipex? • Use caution when driving, operating machinery, or performing other hazardous activities. Amphetamine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Do not take Adipex late in the day. A dose taken too late in the day can cause insomnia. What are the possible side effects of Adipex? • If you experience any of the following serious side effects, stop taking Adipex and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or · hallucinations, abnormal behavior, or confusion. • Other, less serious side effects may be more likely to occur. Continue to take Adipex and talk to your doctor if you experience · restlessness or tremor, · nervousness or anxiety, · headache or dizziness, · insomnia, · dry mouth or an unpleasant taste in your mouth, · diarrhea or constipation, or · impotence or changes in your sex drive. • Adipex is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Adipex? • You cannot take Adipex if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days. • Changes in insulin and other diabetes drug therapies may be necessary during treatment with Adipex. • Adipex may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine. • Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of Adipex. • Drugs other than those listed here may also interact with Adipex. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Where can I get more information? • Your pharmacist has more information about Adipex written for health professionals that you may read. -------------------------------------------------------------------------------- • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Tell your doctor your complete medical history especially if you have high blood pressure, an over-active thyroid, glaucoma, diabetes or emotional problems. Consult with your doctor if you think you are pregnant or before breast-feeding. Alcohol can increase unwanted side effects of dizziness. Limit alcohol use. This drug is not recommended for use in children. Consult your doctor or pharmacist for further information The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. The following information is a summary about Adipex®.It is not intended to replace a doctor's instructions. Each tablet of ADIPEX-P contains 37.5 milligrams of phentermine. Each blue and white, oblong scored tablet is embossed with “ADIPEX-P” and “9”-“9”. The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with “ADIPEX-P”-“37.5” on the cap and two stripes on the body using dark blue ink. HOW DOES ADIPEX-P WORK? Drugs of this class are thought to suppress appetite via a central mechanism (appetite centers in the brain) although this has mechanism has not been clearly proven. HOW TO TAKE ADIPEX-P: This medication is best taken on an empty stomach; one hour before breakfast each morning. Because this medication may cause sleeplessness, avoid taking a dose late in the day. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is generally not recommended. HOW EFFECTIVE IS ADIPEX-P? ADIPEX-P is effective therapy for the obese patient who needs to loose weight to decease diseases associated with significant overweight. The magnitude of the weight loss will depend on the degree of concomitant caloric restriction and the use of a graded exercise program. HOW LONG CAN I CONTINUE TO USE ADIPEX-P? ADIPEX-P is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of ADIPEX-P after a few weeks of treatment, which is when you should be well on your way to a new lifestyle and ready to stop ADIPEX-P. Appetite suppressants are not a substitute for proper diet. For maximum effects, this must be used in conjunction with a diet and exercise program. SORTING THROUGH GENERIC VS. BRAND NAME DRUGS: When a pharmaceutical company develops a new drug, it gives the drug two names. The first, its generic name represents the chemical structure or chemical form of the drug. The generic name of a drug never changes. In this case the generic name of these drugs we are discussing below is PHENTERMINE. The second name given to a drug is its brand name. This is the name given to the medicine by the pharmaceutical company and has nothing to do with its chemical form. The brand names of the drugs we are discussing are ADIPEX-P and IONAMIN. They are both fairly similar in that they are composed of PHENTERMINE, and subsequently given different names by the companies that manufacturer them. No other pharmaceutical company can ever use the brand name of the drug at any time. PHENTERMINE HYDROCHLORIDE (GENERIC NAME) - ADIPEX-P AND IONAMIN (BRAND NAMES): PHENTERMINE, the generic name for ADIPEX-P and IONAMIN comes in immediate release or time-release formulas. Immediate release pills enter your blood stream as soon as you take them, and time-release capsules release their medication into your body over an extended period of time, generally 8 or 12 hours. As you can see, there are many popular brand names of PHENTERMINE. Nonetheless, all of the above named compounds are considered clinically equivalent in producing weight loss. IONAMIN IONAMIN is PHENTERMINE set in resin. The resin allows the compound to be released slowly into the blood stream. Some patients prefer it because they believe it to be associated with fewer side effects, others do not. It is the only PHENTERMINE resin on the market. It comes in 30 mg and 15 mg capsules. The 15 mg capsule is gray and yellow, the 30 mg capsule is all yellow. Each capsule is labeled "IONAMIN". ADIPEX-P VS. XENICAL: PHENTERMINE is an appetite suppressant. XENICAL inhibits fat absorption into the body. So both may be used in conjunction with each other for those who are seriously obese. DRUG INTERACTIONS: Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take high blood pressure medicine or MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine) or any other weight loss medicine. Decongestants are commonly found in over-the-counter cough and cold medicine.[back to top] SIDE EFFECTS: MILD: Blurred vision, dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other adverse events include central nervous system effects, gastrointestinal disturbances, and changes in libido. If these effects persist or become bothersome, you may have to discontinue use. Exercise caution when prescribing anti-obesity drugs for patients with hypertension. If this medication makes you dizzy or lightheaded, avoid driving or engaging in activities requiring alertness. Alcohol can increase unwanted side effects of dizziness. Limit its use. MODERATE: Chest pain, pounding heart, difficulty urinating, breathing difficulties or swelling while taking this medication. SEVERE: Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine (phen-fen) or dexfenfluramine. The possibility of an association between PPH and the use of ADIPEX-P alone cannot be ruled out. CONTRAINDICATIONS: ADIPEX-P is contraindicated in patients with arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. Phentermine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an 'anorectic' or 'anorexigenic' drug. Phentermine sti Adipex is used for the short-term treatment of obesity. Adipex comes in tablets and is taken as a single daily dose in the morning or three times a day 30 minutes before meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Adipex exactly as directed. Adipex can be habit-forming. Do not take a larger dose of Adipex, take it more often, or for a longer period than your doctor tells you to. To prevent side effects, Adipex should be taken with meals. Take the missed dose of Adipex as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose of Adipex and continue your regular dosing schedule. Do not take a double dose of Adipex to make up for a missed one. Dietary instructions Follow the diet and exercise program your doctor has given you. Adipex works best in combination with a diet program. Storage of Adipex Keep Adipex medication in the container it came in, tightly closed, and out of reach of children. Store Adipex at room temperature and away from excess heat and moisture amd not in the bathroom. Phentermine is a phenethylamine primarily used as an appetite suppressant. It is typically prescribed for individuals who are at increased medical risk because of their weight, as opposed to cosmetic weight loss. Phentermine is sold either as an immediate-release formulation (Adipex®) or as a slow-release resin (Ionamin®, Duromine® in Australia and New Zealand). History Phentermine is one of two drugs in the Fen-phen anti-obesity medication, the other being fenfluramine or dexfenfluramine. Fenfluramine was withdrawn from the U.S. market in 1997 after reports of valvular heart disease and pulmonary hypertension. Phentermine is still available by itself in most countries, including the U.S. However, because it is similar to the amphetamines, individuals may develop an addiction to it. Hence, it is classified as a controlled substance in many countries. Internationally, phentermine is a schedule IV drug under the Convention on Psychotropic Substances (PDF file). In the United States, it is classified as a Schedule IV controlled substance under the Controlled Substances Act. Mechanism of action Phentermine, as many other prescription drugs, works with neurotransmitters in the brain. It is a centrally-acting stimulant chemically related to the amphetamines. It stimulates neuron bundles to release a particular group of neurotransmitters known as catecholamines; these include dopamine, epinephrine (also known as adrenalin), and norepinephrine (noradrenaline). The anorectic activity seen with these compounds would thus seem likely due to this effect on Central Nervous System, which is consistent with current knowledge about Central Nervous System systems and feeding behavior. This is the same mechanism of action as other stimulant appetite suppresants such as diethylpropion, and phendimetrazine. The neurotransmitters signal a fight-or-flight response in the body which, in turn, puts a halt to the hunger signal. As a result, it causes a loss in appetite because the brain does not receive the hunger message. Clinical use Generally, it is recommended by the Food and Drug Administration (FDA) that phentermine should be used short-term (usually interpreted as 'up to 12 weeks'), while following nonpharmacological approaches to weight loss such as healthy dieting and exercise. However, recommendations limiting its use for short-term treatment may be controversial. One reason given behind limiting its use to 12 weeks is drug tolerance, whereby phentermine loses its appetite-suppressing effects after the body adjusts to the drug. On the contrary, it has been shown that phentermine did not lose effectiveness in a 36-week trial (PMID 11054601). Due to the risk of insomnia, it is generally recommended that the drug be taken either before breakfast or 1-2 hours after breakfast. Side effects Generally, phentermine appears to be relatively well tolerated.[1] It can produce side effects consistent with its tachycardia, increased alertness, but the incidence and magnitude of these appear to be less than with the amphetamines. Because phentermine acts through sympathomimetic pathways, the drug ug on a long-term basis may develop euphoria and a psychological addiction Contraindications Phentermine should generally be avoided in patients with: Agitation Allergy/Hypersensitivity to other sympathomimetic amines Atherosclerosis Cardiovascular disease Glaucoma High blood pressure Hyperthyroidism Previous history of drug abuse Additionally, this drug should not be used at the same time or within 14 days following the use of monoamine oxidase inhibitors. Internet Notoriety Recently, phentermine has drawn the ire of many internet users. The medication is one of the most commonly used terms in spam e-mails and bulletin board postings by bots. Adipex-P Capsules Manufacturer: Ga DESCRIPTION Phentermine hydrochloride USP has the chemical name of (alpha),(alpha)-Dimethylphenethylamine hydrochloride. The structural formula is as follows: Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether. ADIPEX-P®, an anorectic agent for oral administration, is available as a capsule or tablet containing 37.5 mg ofphentermine hydrochloride (equivalent to 30 mg ofphentermine base). ADIPEX-P® Capsules contain the inactive ingredients Corn Starch, Gelatin, Lactose Monohydrate, Magnesium Stearate, Titanium Dioxide, Black Iron Oxide, FD&C Blue #1, FD&C Red #40 and D&C Red #33. ADIPEX-P® Tablets contain the inactive ingredients Corn Starch, Lactose (Anhydrous), Magnesium Stearate, Microcrystalline Cellulose, Pregelatinized Starch, Sucrose, and FD&C Blue #1. CLINICAL PHARMACOLOGY ADIPEX-P® is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics." It has not been established that the action of such drugs in treating obesity is primarily one of appetite suppression. Other central nervous system actions, or metabolic effects, may be involved, for example. Adult obese subjects instructed in dietary management and treated with "anorectic" drugs lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a fraction of a pound a week. The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. The possible origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed. Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of obesity is measured in years, whereas the studies cited are restricted to a few weeks' duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. INDICATIONS AND USAGE ADIPEX-P® (phentermine hydrochloride) is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index >/=30 kg/m 2 , or >/=27 kg/m 2 in the presence of other risk factors (e.g., hypertension, diabetes, hyperlipidemia). Below is a chart of Body Mass Index (BMI) based on various heights and weights. BMI is calculated by taking the patient's weight, in kilograms (kg), divided by the patient's height, in meters (m), squared. Metric conversions are as follows: pounds ? 2.2 = kg; inches ? 0.0254 = meters. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY ) should be measured against possible risk factors inherent in their use such as those described below. CONTRAINDICATIONS Advanced arteriosclerosis, cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma. Agitated states. Patients with a history of drug abuse. During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result). WARNINGS ADIPEX-P® is indicated only as short-term monotherapy for the management of exogenous obesity. The safety and efficacy of combination therapy with phentermine and any other drug products for weight loss, including selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Therefore, coadministration of these drug products for weight loss is not recommended. Primary Pulmonary Hypertension (PPH)--a rare, frequently fatal disease of the lungs--has been reported to occur in patients receiving a combination of phentermine with fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken phentermine alone. The initial symptom of PPH is usually dyspnea. Other initial symptoms include: angina pectoris, syncope or lower extremity edema. Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema. Valvular Heart Disease: Serious regurgitant cardiac valvular disease, primarily affecting the mitral, aortic and/or tricuspid valves, has been reported in otherwise healthy persons who had taken a combination of phentermine with fenfluramine or dexfenfluramine for weight loss. The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. The possibility of an association between valvular heart disease and the use of phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken phentermine alone. Tolerance to the anorectic effect usually develops within a few weeks. When this occurs, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued. ADIPEX-P® may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly. DRUG ABUSE AND DEPENDENCE ADIPEX-P® is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of ADIPEX-P® should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia. Usage with Alcohol: Concomitant use of alcohol with ADIPEX-P® may result in an adverse drug interaction. PRECAUTIONS General Caution is to be exercised in prescribing ADIPEX-P® (phentermine hydrochloride) for patients with even mild hypertension. Insulin requirements in diabetes mellitus may be altered in association with the use of ADIPEX-P® and the concomitant dietary regimen. ADIPEX-P® may decrease the hypotensive effect of guanethidine. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage. Carcinogenesis, Mutagenesis, Impairment of Fertility: Studies have not been performed with ADIPEX-P® (phentermine hydrochloride) to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. Pregnancy--Teratogenic Effects: Pregnancy Category C. Animal reproduction studies have not been conducted with ADIPEX-P®. It is also not known whether ADIPEX-P® can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. ADIPEX-P® should be given to a pregnant woman only if clearly needed. Nursing Mothers Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Pediatric Use Safety and effectiveness in pediatric patients have not been established. ADVERSE REACTIONS Cardiovascular: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease (see WARNINGS ), palpitation, tachycardia, elevation of blood pressure. Central Nervous System: Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache; rarely psychotic episodes at recommended doses. Gastrointestinal: Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Allergic: Urticaria. Endocrine: Impotence, changes in libido. OVERDOSAGE Manifestations of acute overdosage with phentermine include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma. Management of acute phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases phentermine excretion. Intravenous phentolamine (Regitine®, CIBA) has been suggested for possible acute, severe hypertension, if this complicates phentermine overdosage. DOSAGE AND ADMINISTRATION Exogenous Obesity: Dosage should be individualized to obtain an adequate response with the lowest effective dose. The usual adult dose is one capsule or tablet (37.5 mg) daily, administered before breakfast or 1-2 hours after breakfast. For tablets, the dosage may be adjusted to the patient's need. For some patients ? tablet (18.75 mg) daily may be adequate, while in some cases it may be desirable to give ? tablet (18.75 mg) two times a day. Late evening medication should be avoided because of the possibility of resulting insomnia. Phentermine is not recommended for use in patients sixteen (16) years of age and under. HOW SUPPLIED Available in tablets and capsules containing 37.5 mgphentermine hydrochloride (equivalent to 30 mgphentermine base). Each blue and white, oblong, scored tablet is debossed with "ADIPEX-P" and "9"-"9". The #3 capsule has an opaque white body and an opaque bright blue cap. Each capsule is imprinted with "ADIPEX-P" - "37.5" on the cap and two stripes on the body using dark blue ink. Tablets are packaged in bottles of 30 (NDC 57844-009-56); 100 (NDC 57844-009-01); and 1000 (NDC 57844-009-10). Capsules are packaged in bottles of 100 (NDC 57844-019-01). Store at controlled room temperature 15°-30°C (59°-86°F) (see USP). Dispense in a tight container as defined in the USP, with a child-resistant closure (as required). Manufactured for: GATE PHARMACEUTICALS Div. of Teva Pharmaceuticals USA Sellersville, PA 18960 Manufactured by: TEVA PHARMACEUTICALS USA Sellersville, PA 18960 Rev. R 11/2000 Visit GATE Pharmaceuticals at: www.gatepharma.com The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products. Why is this medication prescribed?Return to top Phentermine is used, in combination with diet and exercise, to help you lose weight. It works by decreasing your appetite. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. How should this medicine be used?Return to top Phentermine comes in tablets and extended-release capsules. It usually is taken as a single daily dose in the morning or three times a day 30 minutes before meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phentermine exactly as directed. Most people take the drug for 3-6 weeks; the length of treatment depends on how you respond to the medication. Phentermine can be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to. To prevent side effects, phentermine should be taken with meals. If you are taking an extended-release (long-acting) product, do not chew or crush the tablet. There are some tablets that can be crushed and mixed with food. What special precautions should I follow?Return to top Before taking phentermine, tell your doctor and pharmacist if you are allergic to phentermine or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac), fluvoxamine (Luvox), guanethidine, insulin, MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)] even if you stopped taking them within the past 2 weeks, medications for weight loss and depression, paroxetine (Paxil), sertraline (Zoloft),and vitamins. tell your doctor if you have or have ever had heart disease, high blood pressure, arteriosclerosis (narrowing of the arteries), hyperthyroidism (overactive thyroid gland), diabetes, glaucoma, or a history of drug abuse. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phentermine, call your doctor. you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you. remember that alcohol can add to the drowsiness caused by this drug. if you have diabetes, you may need a larger dose of insulin while taking phentermine. Call your doctor if you have questions or problems. What special dietary instructions should I follow?Return to top Follow the diet and exercise program your doctor has given you. Phentermine works best in combination with a diet program. What should I do if I forget a dose?Return to top Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. What side effects can this medication cause?Return to top Phentermine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: dry mouth unpleasant taste diarrhea constipation vomiting If you experience any of the following symptoms, call your doctor immediately: increased blood pressure heart palpitations restlessness dizziness tremor insomnia shortness of breath chest pain dizziness swelling of the legs and ankles difficulty doing exercise that you have been able to do If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088]. What storage conditions are needed for this medicine?Return to top Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. In case of emergency/overdoseReturn to top In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911. What other information should I know?Return to top Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to phentermine. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. Brand namesReturn to top Adipex-P® Anoxine-AM® Fastin® Ionamin® Obephen® Obermine® Obestin-30® Phentrol® Adipex-P This page contains drug information on Adipex-P. The information provided includes the following: what is Adipex-P the possible side effects of Adipex-P what happens if you miss a dose of Adipex-P what happens if you overdose with Adipex-P the most important information about Adipex-P how to use Adipex-P other drugs that may affect Adipex-P what to avoid while using Adipex-P Generic Name: phentermine (FEN ter meen) Brand Names: Adipex-P, Fastin, Ionamin, Obenix, Obephen, Oby-Cap, Oby-Trim, Panshape M, Phentercot, Phentride, Pro-Fast HS, Pro-Fast SA, Pro-Fast SR, Teramine, Zantryl What is the most important information I should know about phentermine? • Use caution when driving, operating machinery, or performing other hazardous activities. Phentermine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Phentermine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Do not crush, chew or open any "once-daily" phentermine tablets or capsules. Swallow them whole. What is phentermine? • Phentermine is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an "anorectic" or "anorexigenic" drug. Phentermine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. • Phentermine is used as a short-term supplement to diet and exercise in the treatment of obesity. • Phentermine may also be used for purposes other than those listed in this medication guide. Who should not take phentermine? • You cannot take phentermine if you · have heart disease or high blood pressure; · have arteriosclerosis (hardening of the arteries); · have glaucoma; · have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; or · have a history of drug or alcohol abuse. • Before taking this medication, tell your doctor if you have · problems with your thyroid, · an anxiety disorder, · epilepsy or another seizure disorder, or · diabetes. • You may not be able to take phentermine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. • It is not known whether phentermine will harm an unborn baby. Do not take phentermine without first talking to your doctor if you are pregnant. • It is also not known whether phentermine passes into breast milk. Do not take phentermine without first talking to your doctor if you are breast-feeding a baby. How should I take phentermine? • Take phentermine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. • Phentermine is usually taken once or twice a day before a meal on an empty stomach. • Do not take phentermine in the evening because it may cause insomnia. • Do not crush, chew or open any "once-daily" phentermine tablets or capsules. Swallow them whole. • Never take more of this medication than is prescribed for you. Too much phentermine could be very dangerous to your health. • Store phentermine at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However, if it is almost time for your next dose or if it is already evening, skip the missed dose and take only your next regularly scheduled dose. A dose taken too late in the day will cause insomnia. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a phentermine overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. What should I avoid while taking phentermine? • Use caution when driving, operating machinery, or performing other hazardous activities. Amphetamine may cause dizziness, blurred vision, or restlessness, and it may hide the symptoms of extreme tiredness. If you experience these effects, avoid hazardous activities. • Do not take phentermine late in the day. A dose taken too late in the day can cause insomnia. What are the possible side effects of phentermine? • If you experience any of the following serious side effects, stop taking phentermine and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · an irregular heartbeat or very high blood pressure (severe headache, blurred vision); or · hallucinations, abnormal behavior, or confusion. • Other, less serious side effects may be more likely to occur. Continue to take phentermine and talk to your doctor if you experience · restlessness or tremor, · nervousness or anxiety, · headache or dizziness, · insomnia, · dry mouth or an unpleasant taste in your mouth, · diarrhea or constipation, or · impotence or changes in your sex drive. • Phentermine is habit forming. You can become physically and psychologically dependent on this medication, and withdrawal effects may occur if you stop taking it suddenly after several weeks of continuous use. Talk to your doctor about stopping this medication gradually. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect phentermine? • You cannot take phentermine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days. • Changes in insulin and other diabetes drug therapies may be necessary during treatment with phentermine. • Phentermine may reduce the effects of guanethidine (Ismelin). This could lead to an increase in blood pressure. Tell your doctor if you are taking guanethidine. • Before taking this medication, tell your doctor if you are taking a tricyclic antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), doxepin (Sinequan), nortriptyline (Pamelor), imipramine (Tofranil), clomipramine (Anafranil), protriptyline (Vivactil), or desipramine (Norpramin). These drugs may decrease the effects of phentermine. • Drugs other than those listed here may also interact with phentermine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Carisoprodol is a skeletal muscle relaxant whose active metabolite is meprobamate. Although several case reports have shown that carisoprodol has abuse potential, it continues to be widely prescribed (not so in the United Kingdom where use of benzodiazepines is preferred). Carisoprodol is a colorless, crystalline powder, having a mild, characteristic odor and a bitter taste. It is slightly soluble in water and freely soluble in alcohol, chloroform and acetone. Its solubility is practically independent of pH. It is marketed in the United States under the brand name Soma, and in the United Kingdom and other countries under the brand name Carisoma. This medication may be habit-forming and should be used only by the person it was prescribed for. Carisoprodol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. You may have withdrawal symptoms when you stop using carisoprodol after using it over a long period of time.